67kDa Laminin Receptor (8C5) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52792R |
| Product Name | 67kDa Laminin Receptor (8C5) Monoclonal Antibody |
| Applications |
WB
FCM
IHC-P
IF(ICC)
IHC
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | C terminus human 67kDa Laminin Receptor |
| Clonality | Monoclonal |
| Clone # | 8C5 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 3921 |
| Swiss Prot | P08865 |
| Synonyms | 40S ribosomal protein SA, 37 kDa laminin receptor precursor, 37/67 kDa laminin receptor, 67 kDa laminin receptor, Colon carcinoma laminin-binding protein, Laminin receptor 1, Laminin-binding protein precursor p40, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, 37LRP, LRP/LR, 67LR, LamR, LBP/p40, RPSA |
| Background | Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |
| IHC-P | 1:200-400 |
| IF(ICC) | 1:50-200 |
| IHC | |
