STAT2 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52234r-100uL |
| Product Name | STAT2 Recombinant Antibody |
| Applications |
WB
ICC/IF
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant human STAT2 protein, around N-terminal 1-100aa. |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Target | |
| Gene ID | 6773 |
| Swiss Prot | P52630 |
| Synonyms | P113; ISGF-3; STAT113; Signal transducer and activator of transcription 2; STAT2 |
| Background | Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. |
| Application Dilution | |
| WB | 1:300-5000 |
| ICC/IF | 1:50-100 |
Frequently asked questions
Which applications is STAT2 Recombinant Antibody (bsm-52234R) validated for, and at what dilution?
bsm-52234R is validated for WB (1:300-5000); ICC/IF (1:50-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does STAT2 Recombinant Antibody (bsm-52234R) react with?
Tested reactivity: Human, Mouse.
How should bsm-52234R be stored?
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise STAT2 Recombinant Antibody (bsm-52234R)?
Recombinant human STAT2 protein, around N-terminal 1-100aa.