Neuropilin-1 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52479r-100uL |
| Product Name | Neuropilin-1 Recombinant Antibody |
| Applications |
WB
IHC-P
IHC-F
IF
FLOW-CYT
ICC/IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Human Neuropilin 1 between 900 to C-terminus |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 8829 |
| Swiss Prot | O14786 |
| Synonyms | Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, CD_antigen: CD304, NRP1, NRP, VEGF165R |
| Background | The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
| IF | |
| Flow-Cyt | 1ug/Test |
| ICC/IF | 1:50-100 |
Frequently asked questions
Which applications is Neuropilin-1 Recombinant Antibody (bsm-52479R) validated for, and at what dilution?
bsm-52479R is validated for WB (1:300-5000); IHC-P (1:200-400); IHC-F (1:100-500); IF; Flow-Cyt (1ug/Test); ICC/IF (1:50-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Neuropilin-1 Recombinant Antibody (bsm-52479R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-52479R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise Neuropilin-1 Recombinant Antibody (bsm-52479R)?
Human Neuropilin 1 between 900 to C-terminus