Fibrinogen gamma chain Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54380R-100uL |
| Product Name | Fibrinogen gamma chain Recombinant Antibody |
| Applications |
WB
IHC-P
FCM
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant protein corresponding to human Fibrinogen gamma50-250aa. |
| Clonality | Monoclonal |
| Clone # | 10A1 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Target | |
| Gene ID | 2266 |
| Swiss Prot | P02679 |
| Subcellular location | Secreted |
| Synonyms | Fibrinogen gamma chain; FGG |
| Background | Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is Fibrinogen gamma chain Recombinant Antibody (bsm-54380R) validated for, and at what dilution?
bsm-54380R is validated for WB (1:300-5000); IHC-P (1:200-400); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Fibrinogen gamma chain Recombinant Antibody (bsm-54380R) react with?
Tested reactivity: Human.
How should bsm-54380R be stored?
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Fibrinogen gamma chain Recombinant Antibody (bsm-54380R)?
Recombinant protein corresponding to human Fibrinogen gamma50-250aa.