CD11a Recombinant Antibody
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bsm-60413m-100uL |
| Product Name | CD11a Recombinant Antibody |
| Applications |
FLOW-CYT
ICC/IF
|
| Predicted Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | KLH conjugated synthetic peptide derived from human CD11a |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein G. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 3683 |
| Swiss Prot | P20701 |
| Subcellular location | Cell membrane |
| Synonyms | CD11a; Integrin alpha-L; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; Lymphocyte antigen 15; Ly-15; CD11 antigen-like family member A; CD_antigen; ITAL_HUMAN. |
| Background | ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3(intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. |
| Application Dilution | |
| Flow-Cyt | ICC=1:50 |
| ICC/IF | IF=1:50 |
Frequently asked questions
Which applications is CD11a Recombinant Antibody (bsm-60413M) validated for, and at what dilution?
bsm-60413M is validated for Flow-Cyt (ICC=1:50); ICC/IF (IF=1:50). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bsm-60413M be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise CD11a Recombinant Antibody (bsm-60413M)?
KLH conjugated synthetic peptide derived from human CD11a