PMEL Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61122r-100uL |
| Product Name | PMEL Recombinant Antibody |
| Applications |
WB
IHC-P
IHC-F
IF(IHC-P)
IF
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human PMEL |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | 1mg/ml |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 6490 |
| Swiss Prot | P40967 |
| Subcellular location | Extracellular, Secreted |
| Synonyms | PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV. |
| Background | Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. |
| Application Dilution | |
| WB | 1:500-2000 |
| IHC-P | IHC-P1:100-500 |
| IHC-F | IHC-F1:100-500 |
| IF(IHC-P) | IFIHC-P1:100-500 |
| IF | |
Frequently asked questions
Which applications is PMEL Recombinant Antibody (bsm-61122R) validated for, and at what dilution?
bsm-61122R is validated for WB(WB) (1:500-2000); IHC-P(IHC-P) (1:100-500); IHC-F(IHC-F) (1:100-500); IF(IHC-P)(IF(IHC-P)) (1:100-500); IF. These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does PMEL Recombinant Antibody (bsm-61122R) react with?
Tested reactivity: Human.
How should bsm-61122R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise PMEL Recombinant Antibody (bsm-61122R)?
KLH conjugated synthetic peptide derived from human PMEL