API2/BIRC3 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61124r-20uL |
| Product Name | API2/BIRC3 Recombinant Antibody |
| Applications |
WB
IHC-P
IHC-F
IF(IHC-P)
IF(ICC)
IP
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human BIRC3 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 330 |
| Swiss Prot | Q13489 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | AIP1; API2; BIRC3; CIAP2; HAIP1; IAP homolog C ;RNF49; MIHC; MALT2; Apoptosis inhibitor 2;IAP2. |
| Background | Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. |
| Application Dilution | |
| WB | 1:500-2000 |
| IHC-P | IHC-P1:50-200 |
| IHC-F | IHC-F1:50-200 |
| IF(IHC-P) | IFIHC-P1:50-200 |
| IF(ICC) | IFICC1:50-100 |
| IP | IP1:20-50 |
Frequently asked questions
Which applications is API2/BIRC3 Recombinant Antibody (bsm-61124R) validated for, and at what dilution?
bsm-61124R is validated for WB(WB) (1:500-2000); IHC-P(IHC-P) (1:50-200); IHC-F(IHC-F) (1:50-200); IF(IHC-P)(IF(IHC-P)) (1:50-200); IF(ICC)(IF(ICC)) (1:50-100); IP(IP) (1:20-50). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does API2/BIRC3 Recombinant Antibody (bsm-61124R) react with?
Tested reactivity: Human.
How should bsm-61124R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise API2/BIRC3 Recombinant Antibody (bsm-61124R)?
KLH conjugated synthetic peptide derived from human BIRC3