ASPP2 Recombinant Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61402r-biotin-100uL |
| Product Name | ASPP2 Recombinant Antibody, Biotin Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human TP53BP2 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 7159 |
| Swiss Prot | Q13625 |
| Subcellular location | Nucleus |
| Synonyms | 53BP2; ASPP2; p53BP2; PPP1R13A; Tp53bp2. |
| Background | Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. |
| Application Dilution | |
| WB | 1:500-2000 |
Frequently asked questions
Which applications is ASPP2 Recombinant Antibody, Biotin Conjugated (bsm-61402R-Biotin) validated for, and at what dilution?
bsm-61402R-Biotin is validated for WB(WB) (1:500-2000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ASPP2 Recombinant Antibody, Biotin Conjugated (bsm-61402R-Biotin) react with?
Tested reactivity: Human.
How should bsm-61402R-Biotin be stored?
Store at -20°C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ASPP2 Recombinant Antibody, Biotin Conjugated (bsm-61402R-Biotin)?
KLH conjugated synthetic peptide derived from human TP53BP2