NUMB Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61410r-100uL |
| Product Name | NUMB Recombinant Antibody |
| Applications |
WB
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human NUMB |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 8650 |
| Swiss Prot | P49757 |
| Subcellular location | Cell membrane |
| Synonyms | c14_5527; h Numb; Numb; Numb homolog; S171. |
| Background | Numb acts as a negative regulator of Notch signaling by promoting ubiquitination and degradation of Notch. The protein is asymmetrically segregated into one daughter cell during cell division, producing two daughter cells with different responses to Notch signaling and different cell fates. The localization of Numb can also be regulated by G-protein coupled receptor (GPCR) and PKC signaling. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is NUMB Recombinant Antibody (bsm-61410R) validated for, and at what dilution?
bsm-61410R is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does NUMB Recombinant Antibody (bsm-61410R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-61410R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise NUMB Recombinant Antibody (bsm-61410R)?
KLH conjugated synthetic peptide derived from human NUMB