DR5 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61496r-100uL |
| Product Name | DR5 Recombinant Antibody |
| Applications |
WB
IP
FLOW-CYT
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human DR5 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 8795 |
| Swiss Prot | O14763 |
| Synonyms | Death receptor 5; TRAIL receptor 2; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9. |
| Background | Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. |
| Application Dilution | |
| WB | 1:300-5000 |
| IP | FCM1:20-100 |
| Flow-Cyt | IP1-2ug |
Frequently asked questions
Which applications is DR5 Recombinant Antibody (bsm-61496R) validated for, and at what dilution?
bsm-61496R is validated for WB (1:300-5000); FCM (1:20-100); IP (1-2ug). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does DR5 Recombinant Antibody (bsm-61496R) react with?
Tested reactivity: Human.
How should bsm-61496R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise DR5 Recombinant Antibody (bsm-61496R)?
KLH conjugated synthetic peptide derived from human DR5