DARC Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61907r-100uL |
| Product Name | DARC Recombinant Antibody |
| Applications |
IHC-P
IHC-F
IF(IHC-P)
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Atypical chemokine receptor 1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 2532 |
| Swiss Prot | Q16570 |
| Subcellular location | Cell membrane |
| Synonyms | CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1. |
| Background | Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. |
| Application Dilution | |
| IHC-P | 1:100-500 |
| IHC-F | IHC-F1:100-500 |
| IF(IHC-P) | IFIHC-P1:100-500 |
Frequently asked questions
Which applications is DARC Recombinant Antibody (bsm-61907R) validated for, and at what dilution?
bsm-61907R is validated for IHC-P(IHC-P) (1:100-500); IHC-F(IHC-F) (1:100-500); IF(IHC-P)(IF(IHC-P)) (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does DARC Recombinant Antibody (bsm-61907R) react with?
Tested reactivity: Human, Mouse.
How should bsm-61907R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise DARC Recombinant Antibody (bsm-61907R)?
KLH conjugated synthetic peptide derived from human Atypical chemokine receptor 1