Niemann Pick C1 Like 1 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62028r-100uL |
| Product Name | Niemann Pick C1 Like 1 Recombinant Antibody |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human NPC1L1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 29881 |
| Swiss Prot | Q9UHC9 |
| Subcellular location | Cell membrane |
| Synonyms | NPC1 LIKE 1; NPC1L1. |
| Background | Plays a major role in cholesterol homeostasis.Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte.Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol.Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is Niemann Pick C1 Like 1 Recombinant Antibody (bsm-62028R) validated for, and at what dilution?
bsm-62028R is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Niemann Pick C1 Like 1 Recombinant Antibody (bsm-62028R) react with?
Tested reactivity: Human.
How should bsm-62028R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise Niemann Pick C1 Like 1 Recombinant Antibody (bsm-62028R)?
KLH conjugated synthetic peptide derived from human NPC1L1