TRIM29 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62185r-100uL |
| Product Name | TRIM29 Recombinant Antibody |
| Applications |
WB
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human TRIM29 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 23650 |
| Swiss Prot | Q14134 |
| Subcellular location | Cytoplasm |
| Synonyms | ATDC; TRIM29. |
| Background | Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is TRIM29 Recombinant Antibody (bsm-62185R) validated for, and at what dilution?
bsm-62185R is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does TRIM29 Recombinant Antibody (bsm-62185R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-62185R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise TRIM29 Recombinant Antibody (bsm-62185R)?
KLH conjugated synthetic peptide derived from human TRIM29