GRK6 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62587r-100uL |
| Product Name | GRK6 Recombinant Antibody |
| Applications |
WB
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human GRK6 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 2870 |
| Swiss Prot | P43250 |
| Subcellular location | Cell membrane |
| Synonyms | G protein coupled receptor kinase 6; G protein coupled receptor kinase GRK6; G protein-coupled receptor kinase 6; Gprk6; Grk6. |
| Background | Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro). |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is GRK6 Recombinant Antibody (bsm-62587R) validated for, and at what dilution?
bsm-62587R is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does GRK6 Recombinant Antibody (bsm-62587R) react with?
Tested reactivity: Human, Mouse.
How should bsm-62587R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise GRK6 Recombinant Antibody (bsm-62587R)?
KLH conjugated synthetic peptide derived from human GRK6