HTRA1 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62786r-100uL |
| Product Name | HTRA1 Recombinant Antibody |
| Applications |
WB
ICC/IF
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Serine protease HTRA1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 5654 |
| Swiss Prot | Q92743 |
| Subcellular location | Secreted |
| Synonyms | ARMD7; CARASIL; High-temperature requirement A serine peptidase 1; HtrA; HtrA serine peptidase 1; HTRA1; IGFBP5 protease; ORF480; Protease serine 11 (IGF binding); protease serine 11; PRSS11; Serine protease 11; Serine protease HTRA1. |
| Background | Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. |
| Application Dilution | |
| WB | 1:300-5000 |
| ICC/IF | IFICC1:50-200 |
Frequently asked questions
Which applications is HTRA1 Recombinant Antibody (bsm-62786R) validated for, and at what dilution?
bsm-62786R is validated for WB (1:300-5000); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does HTRA1 Recombinant Antibody (bsm-62786R) react with?
Tested reactivity: Human.
How should bsm-62786R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise HTRA1 Recombinant Antibody (bsm-62786R)?
KLH conjugated synthetic peptide derived from human Serine protease HTRA1