Recombinant Human RS1 Protein, N-GST

Overview
Catalog #	bs-100119p-20ug
Product Name	Recombinant Human RS1 Protein, N-GST
Applications	Others
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant Human LY96 Protein is expressed in E.coli with N-GST.It contains the amino acid sequence of 24-224/224
Storage Buffer	Lyophilized from a solution in 10mM PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	7082
Swiss Prot	O15537
Background	This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]