Recombinant human CD3 epsilon protein, His
Applications
Reactivity
| Overview | |
| Catalog # | bs-41153p-100ug |
| Product Name | Recombinant human CD3 epsilon protein, His |
| Applications |
ELISA
|
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant human CD3 epsilon protein, His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 23-126/207. |
| Storage Buffer | 0.01M TBS(pH7.4) |
| Storage Condition | Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 12501 |
| Swiss Prot | P07766 |
| Background | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]. |