Overview |
bs-41250P |
Recombinant human NLRP3 protein, C-His |
ELISA |
Others |
Specifications |
Unconjugated |
0.01M TBS(pH7.4) |
The product should be stored at -70°C or -20°C. |
Target |
114548 |
Q96P20 |
May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm. |