Recombinant human Lck protein isoform 3 , N-His

Overview
Catalog #	bs-41321p-100ug
Product Name	Recombinant human Lck protein isoform 3 , N-His
Applications	Others
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant human Lck protein isoform 3 is expressed in E.coli with N-His. It contains the amino acid sequence of 222-539/539
Storage Buffer	4M urea (pH9.0) with 20mM Tris-HCl.
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	3932
Swiss Prot	P06239-3
Background	This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008].