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Recombinant SARS-COV-2 N Protein (Omicron, B.1.1.529) N-His

Applications

  • ELISA

Reactivity

  • Others
Overview
Catalog # bs-41494P
Product Name Recombinant SARS-COV-2 N Protein (Omicron, B.1.1.529) N-His
Applications ELISA
Reactivity Others
Specifications
Conjugation Unconjugated
Source Recombinant SARS-COV-2 N Protein (Omicron, B.1.1.529) N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 1-419/419.
Storage Buffer 0.01M TBS(pH7.4)
Storage Condition The product should be stored at -70°C or -20°C.
Target
Gene ID 43740575
Swiss Prot P0DTC9
Background Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.