| Overview |
| bs-41494P-Biotin |
| Recombinant SARS-COV-2 N Protein (Omicron, B.1.1.529) N-His, Biotin Conjugated |
| ELISA |
| Others |
| Specifications |
| Biotin |
| SARS-COV-2 N Protein (Omicron, B.1.1.529) (P13L, E31del, R32del, S33del, R203K, G204R) N-His |
| Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization. |
| The product should be stored at -70°C or -20°C. |
| Target |
| 43740575 |
| P0DTC9 |
| Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
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