Recombinant HIV1 envelope gp41 protein

Overview
Catalog #	bs-41554p-100ug
Product Name	Recombinant HIV1 envelope gp41 protein
Applications	Others
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant HIV1 envelope gp41 protein is expressed in E.coli with N-GST.
Storage Buffer	1M urea in PBS with 25mM K2CO3.
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Background	gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.