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Recombinant human PALB2 protein

Applications

  • Others

Reactivity

  • Others
Overview
Catalog # bs-42066p-100ug
Product Name Recombinant human PALB2 protein
Applications Others
Reactivity Others
Specifications
Conjugation Unconjugated
Source Recombinant human PALB2 protein is expressed in E.coli with His&Trx&S. It contains the amino acid sequence of 841-1186/1186
Storage Buffer 0.01M TBS(pH7.4)
Storage Condition The product should be stored at -70°C or -20°C.
Target
Gene ID 79728
Swiss Prot Q86YC2
Background This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. Essential partner of BRCA2 that promotes the localization and stability of BRCA2. Also enables its recombinational repair and checkpoint functions of BRCA2. May act by promoting stable association of BRCA2 with nuclear structures, allowing BRCA2 to escape the effects of proteosome-mediated degradation.