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Recombinant human CD86 protein, C-His

Applications

  • Others

Reactivity

  • Others
Overview
Catalog # bs-42111p-100ug
Product Name Recombinant human CD86 protein, C-His
Applications Others
Reactivity Others
Specifications
Conjugation Unconjugated
Source Recombinant human CD86 protein is expressed in E.coli with C-His. It contains the amino acid sequence of 27-247/329
Storage Buffer 0.01M TBS(pH7.4)
Storage Condition The product should be stored at -70°C or -20°C.
Target
Gene ID 942.00
Swiss Prot P42081
Background This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].