Recombinant human TLR2 protein, His
Applications
Reactivity
| Overview | |
| Catalog # | bs-42120p-100ug |
| Product Name | Recombinant human TLR2 protein, His |
| Applications | Others |
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant human TLR2 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 21-588/784 |
| Storage Buffer | 0.01M TBS(pH7.4) |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 7097 |
| Swiss Prot | O60603 |
| Background | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq, Jul 2008]. |
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