Recombinant human Calreticulin protein, N-His

Overview
Catalog #	bs-42141p-100ug
Product Name	Recombinant human Calreticulin protein, N-His
Applications	Others
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant human Calreticulin protein is expressed in E.coli with N-His. It contains the amino acid sequence of 18-169/417
Storage Buffer	20mM Tris (pH8.0) with 2M Urea.
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	811
Swiss Prot	P27797
Background	Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]