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Recombinant human CD11a protein, N-His

Applications

  • Others

Reactivity

  • Others
Overview
Catalog # bs-42274P-100ug
Product Name Recombinant human CD11a protein, N-His
Applications Others
Reactivity Others
Specifications
Conjugation Unconjugated
Source Recombinant human CD11a protein is expressed in E.coli with N-His. It contains the amino acid sequence of 26-350/1086
Storage Buffer 0.01M TBS(pH7.4)
Storage Condition The product should be stored at -70°C or -20°C.
Target
Gene ID 3683
Swiss Prot P20701
Background ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]