Recombinant human ESR2 protein, N-Trx-His

Overview
Catalog #	bs-42279P-100ug
Product Name	Recombinant human ESR2 protein, N-Trx-His
Applications	Others
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant human ESR2 protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 1-323/323
Storage Buffer	20mM Tris-HCl (pH9.0) with 8M Urea and 5mM DTT.
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	2100
Swiss Prot	Q92731
Background	This gene encodes a member of the family of estrogenreceptors and superfamily of nuclear receptor transcriptionfactors. The gene product contains an N-terminal DNA binding domainand C-terminal ligand binding domain and is localized to thenucleus, cytoplasm, and mitochondria. Upon binding to17beta-estradiol or related ligands, the encoded protein formshomo- or hetero-dimers that interact with specific DNA sequences toactivate transcription. Some isoforms dominantly inhibit theactivity of other estrogen receptor family members. Severalalternatively spliced transcript variants of this gene have beendescribed, but the full-length nature of some of these variants hasnot been fully characterized. [provided by RefSeq, Jul 2008].