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Recombinant human CYP8B1 protein

Applications

  • Others

Reactivity

  • Others
Overview
Catalog # bs-42311P-100ug
Product Name Recombinant human CYP8B1 protein
Applications Others
Reactivity Others
Specifications
Conjugation Unconjugated
Source Recombinant human CYP8B1 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 22-501/501
Storage Buffer 20mM Tris-Hcl (pH=8.0) with 8M Urea and 0.5M L-Arg.
Storage Condition The product should be stored at -70°C or -20°C.
Target
Gene ID 1582
Swiss Prot Q9UNU6
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008]