Recombinant human HIF-1 Alpha protein, N-Trx-His
Applications
Reactivity
| Overview | |
| Catalog # | bs-42326P-100ug |
| Product Name | Recombinant human HIF-1 Alpha protein, N-Trx-His |
| Applications | Others |
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant human HIF-1 Alpha protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 575-826/826 |
| Storage Buffer | 0.01M TBS(pH7.4) |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 3091 |
| Swiss Prot | Q16665 |
| Background | Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator(ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. |
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