| Overview |
| bs-42407P-100ug |
| Recombinant human CPT1A protein |
| Others |
| Others |
| Specifications |
| Unconjugated |
| Recombinant human CPT1A protein is expressed in E.coliwith N-His. It contains the amino acid sequence of 421-745/773 |
| 20mM Tris-Hcl (pH=8.0) with 8M Urea |
| The product should be stored at -70°C or -20°C. |
| Target |
| 1374 |
| P50416 |
| The mitochondrial oxidation of long-chain fatty acids is nitiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
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