Recombinant human CHAT protein, N-His

Overview
Catalog #	bs-42433p-100ug
Product Name	Recombinant human CHAT protein, N-His
Applications	Others
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant human CHAT protein in E.coli with N-His. It contains the amino acid sequence of 399-748/748
Storage Buffer	20mM Tris-Hcl (pH=8.0) with 8M Urea
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	1103
Swiss Prot	P28329
Background	This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010].