Recombinant human CXADR Protein, N-His
Applications
Reactivity
| Overview | |
| Catalog # | bs-42449p-100ug |
| Product Name | Recombinant human CXADR Protein, N-His |
| Applications | Others |
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant human CXADR Protein in E.coli with N-His. It contains the amino acid sequence of 20-237/365 |
| Storage Buffer | 0.01M TBS(pH7.4) |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 1525 |
| Swiss Prot | P78310 |
| Background | Coxsackie and adenovirus receptor (CAR), also known as CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity. It is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.It is proposed to function as a homophilic cell adhesion molecule and recruits MPDZ to intercellular contact sites. CAR is probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN) through adhesive interactions with AMICA1/JAML located in the plasma membrane of PMN. |
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