Recombinant SARS-Cov-2 Spike RBD protein (XBB.1/Omicron), His (HEK293)
Applications
Reactivity
| Overview | |
| Catalog # | bs-43158p-100ug |
| Product Name | Recombinant SARS-Cov-2 Spike RBD protein (XBB.1/Omicron), His (HEK293) |
| Applications | Others |
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant SARS-Cov-2 Spike RBD protein (XBB.1/Omicron) is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 319-537/1273 |
| Storage Buffer | 0.01M TBS(pH7.4) |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 43740568 |
| Swiss Prot | P0DTC2 |
| Background | The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein. |
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