Recombinant human HLA-E & Beta-2-MG Heterodimer protein, His&Avi (HEK293)

Overview
Catalog #	bs-43161p-100ug
Product Name	Recombinant human HLA-E & Beta-2-MG Heterodimer protein, His&Avi (HEK293)
Applications	Others
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant human HLA-E & Beta-2-MG Heterodimer protein is expressed in HEK293 cell with His&Avi . It contains the amino acid sequence of 22-305/358
Storage Buffer	0.01M TBS(pH7.4)
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	3133
Swiss Prot	P13747
Background	HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]