Recombinant human TGFBR2 protein, C-His (HEK293)
Applications
Reactivity
| Overview | |
| Catalog # | bs-43522p-100ug |
| Product Name | Recombinant human TGFBR2 protein, C-His (HEK293) |
| Applications |
ELISA
|
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant human TGFBR2 protein, C-His (HEK293) protein is expressed in HEK293 with C-His. It contains the amino acid sequence of 23-159/567. |
| Storage Buffer | 0.01M TBS(pH7.4) |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 7048 |
| Swiss Prot | P37173 |
| Background | This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. |