Recombinant human TGFBR2 protein, C-hFc (HEK293)

Overview
Catalog #	bs-43523p-100ug
Product Name	Recombinant human TGFBR2 protein, C-hFc (HEK293)
Applications	ELISA
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant human TGFBR2 protein, C-hFc (HEK293) protein is expressed in HEK293 with C-hFc. It contains the amino acid sequence of 23-159/567.
Storage Buffer	0.01M TBS(pH7.4)
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	7048
Swiss Prot	P37173
Background	This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.