| Overview |
| bs-43523P |
| Recombinant human TGFBR2 protein, C-hFc (HEK293) |
| ELISA |
| Others |
| Specifications |
| Unconjugated |
| Recombinant human TGFBR2 protein, C-hFc (HEK293) protein is expressed in HEK293 with C-hFc. It contains the amino acid sequence of 23-159/567. |
| 0.01M TBS(pH7.4) |
| The product should be stored at -70°C or -20°C. |
| Target |
| 7048 |
| P37173 |
| This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. |
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