Recombinant mouse CD86 protein, C-His (HEK293)
Applications
Reactivity
| Overview | |
| Catalog # | bs-43590p-100ug |
| Product Name | Recombinant mouse CD86 protein, C-His (HEK293) |
| Applications | Others |
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant mouse CD86 protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 24-245/309 |
| Storage Buffer | 0.01M TBS(pH7.4) |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 12524 |
| Swiss Prot | P42082 |
| Background | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]. |
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