Recombinant Human ACE2
OVERVIEW | |
CATALOG # | bs-46001P |
REFERENCE # | ACE_HM401 |
PRODUCT NAME |
Recombinant Human ACE2
|
CONJUGATION | Unconjugated |
SOURCE |
Recombinant human ACE2 is expressed from mammalian with a His-tag and Avi at the C-terminal. It contains Gln18- Ser740. |
EXPRESSION SYSTEM |
HEK293 |
TAG |
His-Avi |
MOLECULAR WEIGHT |
The protein has a predicted MW of 86.5kDa. Due to glycosylation, the protein migrates to 95-110kDa based on Bis-Tris PAGE result. |
ENDOTOXIN |
Less than 1EU per ug by the LAL method. |
PURITY: |
> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
FORMULATION |
Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization. |
STORAGE |
The product should be stored at -70℃ or -20℃. |
TARGET | |
ACCESSION |
Q9BYF1 |
BACKGROUND | ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension. The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. |