Recombinant Human ACE2
| OVERVIEW | |
| CATALOG # | bs-46001P |
| PRODUCT NAME |
Recombinant Human ACE2
|
| CONJUGATION | Unconjugated |
| SOURCE |
Recombinant human ACE2 is expressed from mammalian with a His-tag and Avi at the C-terminal. It contains Gln18- Ser740. |
| EXPRESSION SYSTEM |
HEK293 |
| TAG |
His-Avi |
| MOLECULAR WEIGHT |
The protein has a predicted MW of 86.5kDa. Due to glycosylation, the protein migrates to 95-110kDa based on Bis-Tris PAGE result. |
| ENDOTOXIN |
Less than 1EU per ug by the LAL method. |
| PURITY: |
> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
| FORMULATION |
Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization. |
| STORAGE |
The product should be stored at -70℃ or -20℃. |
| TARGET | |
|
ACCESSION |
Q9BYF1 |
| BACKGROUND | ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension. The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. |