Recombinant SARS-CoV-2 Spike RBD
| OVERVIEW | |
| CATALOG # | bs-46005P |
| REFERENCE # | COV_VM5BD |
| PRODUCT NAME |
Recombinant SARS-CoV-2 Spike RBD
|
| CROSS REACTIVE SPECIES DETAILS |
SARS-CoV-2
|
| CONJUGATION | Unconjugated |
| SOURCE |
SARS-CoV-2 S protein RBD is expressed from mammalian with a Fc tag and Avi at the C-terminal. It contains Arg319-Asn532 |
| EXPRESSION SYSTEM |
HEK293 |
| TAG | Fc-Avi |
| MOLECULAR WEIGHT |
The protein has a predicted MW of 51.7kDa. Due to glycosylation, the protein migrates to 60-62kDa based on Bis-Tris PAGE result. |
| ENDOTOXIN |
Less than 1EU per ug by the LAL method. |
| PURITY: |
> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
| FORMULATION |
Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization. |
| STORAGE |
The product should be stored at -70℃ or -20℃. |
| TARGET | |
|
ACCESSION |
QHD43416.1 |
| BACKGROUND |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |