Recombinant SARS-CoV-2 Spike S1
|CROSS REACTIVE SPECIES DETAILS||
SARS-CoV-2 Spike S1 is expressed from mammalian with a Fc tag and Avi at the C-terminal.
It contains Gln 14-Arg 683.
The protein has a predicted MW of 102.6 kDa. Due to glycosylation, the protein migrates to 130-140KDa based on Bis-Tris PAGE result.
Less than 1EU per ug by the LAL method.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
||Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.|
The product should be stored at -70℃ or -20℃.
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.