| Overview |
| bsm-52005r-percp-Cy5.5-100ul |
| 14-3-3 sigma Monoclonal Antibody, PerCP-Cy5.5 Conjugated |
| IF |
| Human, Mouse, Rat |
| Specifications |
| PerCP-Cy5.5 |
| Rabbit |
| Recombinant human 14-3-3 sigma protein, full length. |
| Monoclonal |
| 2E12 |
| IgG |
| Lot Dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 2810 |
| P31947 |
| 14-3-3 protein sigma; SFN; Epithelial cell marker protein 1; Stratifin; HME1 |
| Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.1 Publication
p53-regulated inhibitor of G2/M progression. |
| Application Dilution |
| IF |
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