| Overview |
| bsm-52021r-bf350-100ul |
| Bcl10 Recombinant Antibody, AbBy Fluor-350 Conjugated |
| WB, IF, Flow-Cyt |
| Human |
| Specifications |
| AbBy Fluor-350 |
| Rabbit |
| Recombinant human Bcl10 protein, around C-terminal 200aa. |
| Monoclonal |
| 3F4 |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 8915 |
| O95999 |
| CLAP; mE10; CIPER; IMD37; c-E10; CARMEN; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; Mammalian CARD-containing adapter molecule E10; BCL10 |
| Involved in adaptive immune response (PubMed:25365219). Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 (PubMed:18264101). |
| Application Dilution |
| WB |
1:300-5000 |
| IF |
|
| Flow-Cyt |
1ug/Test |