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Bcl10 Recombinant Antibody, RBITC Conjugated

Applications

  • WB
  • IF
  • Flow-Cyt

Reactivity

  • Human
Overview
Catalog # bsm-52021r-rbitc-100ul
Product Name Bcl10 Recombinant Antibody, RBITC Conjugated
Applications WB, IF, Flow-Cyt
Reactivity Human
Specifications
Conjugation RBITC
Host Rabbit
Source Recombinant human Bcl10 protein, around C-terminal 200aa.
Clonality Monoclonal
Clone # 3F4
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 8915
Swiss Prot O95999
Synonyms CLAP; mE10; CIPER; IMD37; c-E10; CARMEN; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; Mammalian CARD-containing adapter molecule E10; BCL10
Background Involved in adaptive immune response (PubMed:25365219). Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 (PubMed:18264101).
Application Dilution
WB 1:300-5000
IF
Flow-Cyt 1ug/Test