| Overview |
| bsm-52389r-bf350-100ul |
| N Cadherin Recombinant Antibody, AbBy Fluor-350 Conjugated |
| WB, IF |
| Human, Mouse, Rat |
| Specifications |
| AbBy Fluor-350 |
| Rabbit |
| Recombinant human N Cadherin between 150 to 250 amino acids |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 1000 |
| P19022 |
| Cadherin-2, CDw325, Neural cadherin, CD_antigen: CD325, N-cadherin, CDH2 |
| Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
| IF |
|