| Overview |
| bsm-52746r-rbitc-100ul |
| TSG101 Recombinant Antibody, RBITC Conjugated |
| WB, IF, Flow-Cyt |
| Human, Mouse, Rat |
| Specifications |
| RBITC |
| Rabbit |
| Human TSG101 between 1 to 100 amino acids |
| 30-70/390 |
| Monoclonal |
| 6C3 |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 7251 |
| Q99816 |
| Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101 |
| Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. |
| Application Dilution |
| WB |
1:300-5000 |
| IF |
|
| Flow-Cyt |
1ug/Test |
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