| Overview |
| bsm-52793r-fitc-100ul |
| TFRC Recombinant Antibody, FITC Conjugated |
| WB, Flow-Cyt |
| Human, Rat |
| Mouse |
| Specifications |
| FITC |
| Rabbit |
| Human Transferrin Receptor between 100 to 450 amino acids |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| P02786 |
| P02786 |
| Transferrin receptor protein 1, T9, p90, CD_antigen: CD71, TR, TfR, TfR1, Trfr, TFRC |
| Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
| Application Dilution |
| WB |
1:300-5000 |
| Flow-Cyt |
1ug/Test |
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