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ITPR1 (5G10) Monoclonal Antibody

Applications

  • IHC-P

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-54046R
Product Name ITPR1 (5G10) Monoclonal Antibody
Applications IHC-P
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Human IP3 receptor aa 1770-1900
Clonality Monoclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store for 1 year at -20C from date of shipment. Store for 1 year at -20C from date of shipment.
Target
Gene ID 3708
Swiss Prot Q14643
Synonyms Inositol 1,4,5-trisphosphate receptor type 1, IP3 receptor isoform 1, Type 1 inositol 1,4,5-trisphosphate receptor, IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1; IP3 Receptor.
Background Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
Application Dilution
IHC-P 1:200-400