| Overview |
| bsm-54065r-bf488-100ul |
| Reelin Recombinant Antibody, AbBy Fluor-488 Conjugated |
| WB |
| Human, Rat |
| Specifications |
| AbBy Fluor-488 |
| Rabbit |
| Human Reelin aa 241-340 |
| Monoclonal |
| 4C3 |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 5649 |
| P78509 |
| Secreted |
| Reelin, RELN |
| Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation. |
| Application Dilution |
| WB |
=1:500-2000 |
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