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Trefoil factor 1 Recombinant Antibody, Cy3 Conjugated

Applications

  • WB
  • IF
  • Flow-Cyt

Reactivity

  • Human
Overview
Catalog # bsm-54139r-cy3-100ul
Product Name Trefoil factor 1 Recombinant Antibody, Cy3 Conjugated
Applications WB, IF, Flow-Cyt
Reactivity Human
Specifications
Conjugation Cy3
Host Rabbit
Source Synthetic peptide within human TFF1 aa 50-100
Clonality Monoclonal
Clone # 4B1
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 7031
Swiss Prot P04155
Synonyms Trefoil factor 1; Breast cancer estrogen-inducible protein; PNR-2; Polypeptide P1 A; Protein pS2; hP1 A; BCEI; PS2; TFF1; Estrogen Inducible Protein pS2.
Background Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. TFF1 has been found to be a stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. TFF1 may inhibit the growth of calcium oxalate crystals in urine.
Application Dilution
WB 1:300-5000
IF
Flow-Cyt 1ug/Test